Benzalkonium Chloride Nasal Spray Side Effects
Benzalkonium chloride nasal spray side effects. What are some other side effects of Benzalkonium Chloride. Prolonged repeated use of nasal decongestants for symptomatic relief of allergic rhinitis often results in rhinitis medicamentosa RM a condition involving rebound swelling and additional congestion. Benzalkonium chloride has toxic effects on human respiratory mucosa and human neutrophils.
Most decongestant sprays contain the preservative benzalkonium chloride BKC which causes toxic reactions in the nose eyes ears and lungs and may exacerbate the symptoms of allergic rhinitis. If this effect persists or worsens tell your doctor or pharmacist promptly. 1Department of Otolaryngology Head and Neck Surgery Haukeland University Hospital Bergen Norway.
The effects of such preservatives on the nasal mucosa have not been clearly defined although benzalkonium chloride 005 has been reported to produce a consistent and significant increase in. It was found that only the subjects who were treated with the combination of oxymetazoline nasal spray and benzalkonium chloride had increased nasal stuffiness estimated by symptom scores and measurements of nasal mucosa swelling after 10 days of treatment. Berg OH1 Henriksen RN Steinsvåg SK.
I think this study is important because it is the first time we are aware of that someone has shown that there are deleterious side effects to saline nasal spray. It has been suggested that benzalkonium chloride may be harmful to the nasal mucosa. Of those analyzed we believe that the most important symptoms for determining the safety and tolerance of the preservative-free acidified solution nasal spray are nasal burning smell disturbance taste disturbance nasal bleeding purulent rhinorrhea runny nose with pus sore throat need to blow nose sneezing runny nose postnasal discharge thick nasal discharge ear fullness ear pain and facial.
This preservative is known to cause side effects within the nose such as a decrease in the mucociliary transport within the nose the noses self-cleaning feature irritation of the lining of the nose and decreased the function of infection-fighting white blood cells within the nose. However if the inside of your nose is very dry and irritated stinging may occur. Adverse effects of benzalkonium chloride on the nasal mucosa.
All drugs may cause side effects. Products that contain benzalkonium chloride BAK a commonly used preservative in various personal care products ophthalmic solutions nasal sprays and cleaning agents should be used with caution in people with compromised skin barriers according to a recent study. Ototoxicity can occur when benzalkonium chloride is applied to the ear 8.
The effect of a benzalkonium chloride-containing nasal spray on human respiratory mucosa in vitro as a function of concentration and time of action. However many people have no side effects or only have minor side effects.
Sensory systems Ocular surface disturbances secondary to the toxic effects of benzalkonium chloride lead to a shift in inflammatory mediators and migration of Langerhans cells.
Ototoxicity can occur when benzalkonium chloride is applied to the ear 8. Sensory systems Ocular surface disturbances secondary to the toxic effects of benzalkonium chloride lead to a shift in inflammatory mediators and migration of Langerhans cells. The effect of a benzalkonium chloride-containing nasal spray on human respiratory mucosa in vitro as a function of concentration and time of action. External liquid external solution. Recent studies demonstrate the effects of nasal sprays containing BKC or the decongestant oxymetazoline OXY in the development of RM. If your doctor has directed you to. It has been suggested that benzalkonium chloride may be harmful to the nasal mucosa. Products that contain benzalkonium chloride BAK a commonly used preservative in various personal care products ophthalmic solutions nasal sprays and cleaning agents should be used with caution in people with compromised skin barriers according to a recent study. What are some side effects that I need to call my doctor about right away.
The effect of a benzalkonium chloride-containing nasal spray on human respiratory mucosa in vitro as a function of concentration and time of action. Even though it may be rare some people may have very bad and sometimes deadly side effects when taking a drug. Applies to benzalkonium chloride topical. Products that contain benzalkonium chloride BAK a commonly used preservative in various personal care products ophthalmic solutions nasal sprays and cleaning agents should be used with caution in people with compromised skin barriers according to a recent study. Recent studies demonstrate the effects of nasal sprays containing BKC or the decongestant oxymetazoline OXY in the development of RM. The effect of a benzalkonium chloride-containing nasal spray on human respiratory mucosa in vitro as a function of concentration and time of action. Ototoxicity can occur when benzalkonium chloride is applied to the ear 8.
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